Monthly Archives: August 2014

Wolff Rearrangement

Wolff Rearrangement

General Characteristics The rearrangement of the carbenes formed by elimination of nitrogen from diazoketones giving ketenes is known as the Wolff rearrangement. The ketenes are trapped by ...

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Mukaiyama Redox Condensation

Mukaiyama Redox Condensation

General Characteristics The quinone-phosphine redox system can be used to activate alcohols towards esterification, etherification, and other SN2 reactions with various nucleophiles. The reaction is ...

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Fischer Indole Synthesis

Fischer Indole Synthesis

General Characteristics Upon heating under acidic conditions, aryl hydrazones synthesized from aldehydes/ketones and aryl hydrazines undergo sigmatropic rearrangement and aromatization to give ...

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Pfitzner-Moffatt Oxidation

Pfitzner-Moffatt Oxidation

General Characteristics The oxidation of alcohols using the combination of DCC+Brønsted acid+DMSO is known as the Pfitzner-Moffatt oxidation. The active species of this reaction is bulkier than those ...

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