General Characteristics Aromatic nitriles can be synthesized from the corresponding aryl halides using copper(I) cyanide. The reaction tends to require high temperature conditions but is ...
Monthly Archives: January 2016
Thiol-ene Reaction
General Characteristics Thiols and alkenes undergo free-radical mediated S-C bond formation known as thiol-ene reaction. Thanks to its high chemoselectivity and functional group tolerance, it is ...
Thorpe-Ingold Effect
General Characteristics The effect of geminal substitution in linear molecules that promotes cyclization is referred to as the Thorpe-Ingold effect (aka. gem-dialkyl effect). General References ...
Bioconjugation
General Characteristics Bioconjugation is a process of covalently functionalizing biological molecules. It is most relevant to protein chemistry and is one of the newest topics in reaction ...