General Characteristics Anilines can be converted into aminophenols by the reaction called the Boyland-Sims oxidation. Ortho-hydroxylated products are usually obtained preferentially. The oxidation ...
Monthly Archives: June 2017
Mukaiyama Condensation Reagent
General Characteristics First introduced in 1970’s, 2-halo-N-alkylpyridinium salts are called the Mukaiyama reagent and used for condensation reactions such as esterification and amide bond ...
Betti Reaction
General Characteristics The three component condensation reaction among aldehydes, amines, and phenols is known as the Betti reaction. This reaction is the phenol version of the Mannich reaction. ...
Pinner Reaction
General Characteristics The treatment of nitriles with HCl-anhydrous alcohol generates imidate salts, which can be converted into amidines and orthoesters using amines and alcohols, respectively. The ...
Hell-Volhard-Zelinsky Reaction
General Characteristics The classical method to convert carboxylic acids into α-haloacyl halides using phosphorus(III) halide is known as the Hell-Volhard-Zelinsky reaction. General References Hell, ...
Norrish Reaction
General Characteristics Upon photo-irradiation, carbonyl compounds undergo carbon-carbon bond cleavage reactions via biradical intermediates. The first type involves the formation of acyl radicals ...