Tag Archives: condensation

Condensation Reagent

Condensation Reagent

General Characteristics Esters and amides (peptides) can be obtained by condensing carboxylic acids with alcohols and amines under strongly acidic conditions (Fischer method). However, epimerization ...

Read more
Mukaiyama Condensation Reagent

Mukaiyama Condensation Reagent

General Characteristics First introduced in 1970’s, 2-halo-N-alkylpyridinium salts are called the Mukaiyama reagent and used for condensation reactions such as esterification and amide bond ...

Read more
Classical Aldol Reaction

Classical Aldol Reaction

General Characteristics -In aldol reactions, the enol or the enolate of a ketone attacks an aldehyde or another ketone to generate a β-hydroxyketone (“aldol”). In the most classical procedure, the ...

Read more
Thorpe-Ziegler Reaction

Thorpe-Ziegler Reaction

Characteristics The reaction between a nitrile and an alkoxide base leads to the formation of a β-iminonitrile from which an α-cyanoketone is obtained by mild acid hydrolysis. This reaction is ...

Read more