General Characteristics The organocuprate reagents [R2CuLi] prepared from copper(I) sources and two equivalents of organolithiums work as strong nucleophiles in 1,4-additions to α,β-unsaturated ...
Tag Archives: conjugate addition
Michael Addition
General Characteristics The Michael reaction originally meant the 1,4-addition (conjugate addition) of simple anionic carbons to the electron poor double bonds conjugated to carbonyl groups. Today’s ...